We study epigenetic events that contribute to cellular differentiation and cancer. To address these fundamental questions, we develop and apply innovative cutting-edge single-molecule technologies. The activity of genes, and thus the establishment and maintenance of a cell’s identity, is regulated by their cell type-specific chromatin organization. Chromatin structure is constantly changing in response to developmental and environmental cues; this dynamic regulation is the basis for cellular plasticity.
Epigenetic deregulation is common in a wide spectrum of diseases, from developmental disorders to many types of cancers. We develop novel methodologies with the goal of paving the way towards deeper understanding of chromatin regulation, as well as the development of therapeutic and diagnostic tools.
Required elements for research-based postdoc applications
We are looking for highly motivated postdocs with experience in molecular biology and/or optics and imaging. Candidates should show successful track record during their PhD, with at least one first-author publication in peer-reviewed journal.
Max and Lillian Candiotty Building
Weizmann Institute of Science