The Shalev-Benami lab focuses on visualizing the complex architectures of macromolecular assemblies, with the aim of learning how their complicated structures contribute to their ability to mediate cellular functions. To do this we use a combination of structural, biophysical and biochemical techniques with an emphasis on high-resolution electron cryo- microscopy (cryo-EM). Our current emphasis is on signaling pathways in the CNS in health and disease.
Required elements for research-based postdoc applications:
This is an opportunity for a talented and self-motivated structural biologist to undertake structural studies of macromolecular complexes through cryo-EM and cryo-ET. Applicants should have prior experience in biochemistry (protein purification) and structural biology (crystallography and/or cryo-EM). Cryo-ET and cell culture work will be an advantage.
Address: Department of Structural Biology, Helen and Milton A. Kimmelman Building, Room 665
Weizmann Institute of Science
Rehovot 761001, Israel.